2-Fluorophenylacetyl chloride
2-Fluorophenylacetyl chloride
CAS: 451-81-0
Molecular Formula: C8H6ClFO
2-Fluorophenylacetyl chloride - Names and Identifiers
| Name | 2-Fluorophenylacetyl chloride |
| Synonyms | SKL1171 O-fluorobenzene chloride 2-FLUOROPHENYLACETYL CHLORIDE 2-Fluorophenylacetyl chloride Benzeneacetyl chloride, 2-fluoro- 2-(2'-Fluorophenyl)acetyl chloride 2-(2'-FLUOROPHENYL)-ACETYL-CHLORIDE 2-(2-Fluorophenyl)ethanoyl chloride |
| CAS | 451-81-0 |
| EINECS | 240-677-1 |
| InChI | InChI=1/C8H6ClFO/c9-8(11)5-6-3-1-2-4-7(6)10/h1-4H,5H2 |
2-Fluorophenylacetyl chloride - Physico-chemical Properties
| Molecular Formula | C8H6ClFO |
| Molar Mass | 172.58 |
| Density | 1.279g/cm3 |
| Boling Point | 220.096°C at 760 mmHg |
| Flash Point | 86.911°C |
| Vapor Presure | 0.115mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.515 |
2-Fluorophenylacetyl chloride - Introduction
2-Fluorophenylacetyl chloride is an organic compound with the chemical formula C8H6ClFO. It is a colorless to yellow liquid with a pungent odor.
2-Fluorophenylacetyl chloride is mainly used as an important intermediate in organic synthesis. It can be used to prepare chemicals, drugs, dyes, coatings, etc. Its existence can change the activity and selectivity of compounds, so it has a wide range of applications in the field of organic chemistry.
The preparation method of 2-Fluorophenylacetyl chloride is generally obtained by reacting o-fluorobenzoic acid and thionyl chloride. First, o-fluorobenzoic acid and thionyl chloride are mixed under anhydrous conditions, then the reaction is carried out at a higher temperature, and finally the product is obtained by water quenching or water cooling.
Safety precautions are required when using 2-Fluorophenylacetyl chloride. It is an irritating substance and may be harmful to the eyes, skin and respiratory tract. Therefore, direct contact with skin and eyes should be avoided during operation, and it is required to be used under well-ventilated conditions. If you come into contact with the substance, rinse immediately with plenty of water and seek medical help.
In storage, 2-Fluorophenylacetyl chloride should be stored in a sealed container, away from fire and oxidant; avoid contact with air, water, humidity, etc. to prevent unexpected reactions.
2-Fluorophenylacetyl chloride is mainly used as an important intermediate in organic synthesis. It can be used to prepare chemicals, drugs, dyes, coatings, etc. Its existence can change the activity and selectivity of compounds, so it has a wide range of applications in the field of organic chemistry.
The preparation method of 2-Fluorophenylacetyl chloride is generally obtained by reacting o-fluorobenzoic acid and thionyl chloride. First, o-fluorobenzoic acid and thionyl chloride are mixed under anhydrous conditions, then the reaction is carried out at a higher temperature, and finally the product is obtained by water quenching or water cooling.
Safety precautions are required when using 2-Fluorophenylacetyl chloride. It is an irritating substance and may be harmful to the eyes, skin and respiratory tract. Therefore, direct contact with skin and eyes should be avoided during operation, and it is required to be used under well-ventilated conditions. If you come into contact with the substance, rinse immediately with plenty of water and seek medical help.
In storage, 2-Fluorophenylacetyl chloride should be stored in a sealed container, away from fire and oxidant; avoid contact with air, water, humidity, etc. to prevent unexpected reactions.
Last Update：2024-04-09 20:49:11
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Product Name: 2-(2-Fluorophenyl)acetyl chloride Visit Supplier Webpage Request for quotationCAS: 451-81-0
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